I much appreciate the honour of being invited to deliver the first Manson lecture, which, its founder has laid down, is to be devoted to the consideration of some subject of common interest to philosophy and medicine. I cannot think of anything which better fulfils that condition than the neurological approach to the problem of perception. The neurologist holds the bridge between body and mind. Every day he meets with examples of disordered perception and he learns from observing the effects (...) of lesions produced by disease, or by the physiologist's experiments, something of how the neural basis of perception is organized. It is possible to study perception as though this was largely irrelevant. How far that view is right will be for you to judge when I have finished. (shrink)

On a remarkably thin base of evidence – largely the spectral analysis of points of light – astronomers possess, or appear to possess, an abundance of knowledge about the structure and history of the universe. We likewise know more than might even have been imagined a few centuries ago about the nature of physical matter, about the mechanisms of life, about the ancient past. Enormous theoretical and methodological ingenuity has been required to obtain such knowledge; it does not invite easy (...) discovery by the untutored. It may seem odd, then, that we have so little scientific knowledge of what lies closest at hand, apparently ripe for easy discovery, and of greatest importance for our quality of life: our own conscious experience – our sensory experiences and pains, for example, our inner speech and imagery, our felt emotion. Scientists know quite a bit about human visual capacities and the brain processes involved in vision, much less about the subjective experience of seeing; a fair bit about the physiology of emotion, almost nothing about its phenomenology. Philosophers began in earnest in the seventeenth and eighteenth centuries to describe and classify our patterns of conscious experience. John Locke, for instance, divided experienced “ideas” into those that arise from sensation and those that arise from reflection, and he began to classify them into. (shrink)

Many debates about the moral status of things—for example, debates about the natural rights of human fetuses or nonhuman animals—eventually migrate towards a discussion of the capacities of the things in question—for example, their capacities to feel pain, think, or love. Yet the move towards capacities is often controversial: if a human’s capacities are the basis of its moral status, how could a human having lesser capacities than you and I have the same "serious" moral status as you and I? (...) This book answers this question by arguing that if something is human, it has a set of typical human capacities; that if something has a set of typical human capacities, it has serious moral status; and thus all human beings have the same sort of serious moral status as you and I. Beginning from what our common intuitions tell us about situations involving "temporary incapacitation"—where a human organism has, then loses, then regains a certain capacity—this book argues for substantive conclusions regarding human fetuses and embryos, humans in a permanent vegetative state, humans suffering from brain diseases, and humans born with genetic disorders. Since these conclusions must have some impact on our ongoing moral and political debates about the proper treatment of such humans, this book will be useful to professionals and students in philosophy, bioethics, law, medicine, and public policy. (shrink)

In his novel Remembrance of Things Past, Marcel Proust argues that conventional descriptions of the phenomenology of consciousness are incomplete because they focus too much on the highly-salient sensory information that dominates each moment of awareness and ignore the network of associations that lies in the background. In this paper, I explicate Proust’s theory of conscious experience and show how it leads him directly to a theory of aesthetic perception. Proust’s division of awareness into two components roughly corresponds to William (...) James’ division of the stream of thought into a “nucleus” and “fringe.” Proust argues that the function of art is to evoke the underlying associative network indirectly in the mind of the observer by using carefully chosen sensory surfaces to control the stream of thought. I propose a possible neural basis for this Proustian/Jamesian phenomenology, and argue that the general principles of Proustian aesthetics can be applied to all forms of art. I conclude that a scientific theory of art should follow in a straightforward manner from a scientific theory of consciousness. (shrink)

In this book, the authors present current research in the study of the philosophy of the mind. Topics discussed in this compilation include the concepts of hope and belief; how consciousness builds the subject through relating and human behaviour; analysing the neurophysiological mechanism of qigong on the mind and brain activity; the conscious and unconscious mind and implications for society, religion, and disease; how the mind is shaped by culture; and the power of computational mathematics to explore some of (...) the universal ways by which each human mind builds its image of the world. (shrink)

Steven Pinker has said that one of the most important questions humans can ask of themselves is whether moral progress has occurred or is likely to occur. Buchanan and Powell here address that question, in order to provide the first naturalistic, empirically-informed and analytically sophisticated theory of moral progress--explaining the capacities in the human brain that allow for it, the role of the environment, and how contingent and fragile moral progress can be.

It is largely acknowledged that natural languages emerge not just from human brains but also from rich communities of interacting human brains (Senghas, ). Yet the precise role of such communities and such interaction in the emergence of core properties of language has largely gone uninvestigated in naturally emerging systems, leaving the few existing computational investigations of this issue at an artificial setting. Here, we take a step toward investigating the precise role of community structure in the emergence of linguistic (...) conventions with both naturalistic empirical data and computational modeling. We first show conventionalization of lexicons in two different classes of naturally emerging signed systems: (a) protolinguistic “homesigns” invented by linguistically isolated Deaf individuals, and (b) a natural sign language emerging in a recently formed rich Deaf community. We find that the latter conventionalized faster than the former. Second, we model conventionalization as a population of interacting individuals who adjust their probability of sign use in response to other individuals' actual sign use, following an independently motivated model of language learning (Yang, , ). Simulations suggest that a richer social network, like that of natural (signed) languages, conventionalizes faster than a sparser social network, like that of homesign systems. We discuss our behavioral and computational results in light of other work on language emergence, and other work of behavior on complex networks. (shrink)

William James described the stream of thought as having two components: (1) a nucleus of highly conscious, often perceptual material; and (2) a fringe of dimly felt contextual information that controls the entry of information into the nucleus and guides the progression of internally directed thought. Here I examine the neural and cognitive correlates of this phenomenology. A survey of the cognitive neuroscience literature suggests that the nucleus corresponds to a dynamic global buffer formed by interactions between different regions of (...) the brain, while the fringe corresponds to a set of mechanisms in the frontal and medial temporal lobes that control the contents of this global buffer. A consequence of this account is that there might be conscious imagistic representations that are not part of the nucleus. I argue that phenomenology can be linked to psychology and neuroscience and a meaningful way that illuminates both. (shrink)

Most current theoretical models of dreaming are built around an assumption that dream reports collected on awakening provide unbiased sampling of previous cognitive activity during sleep. However, such data are retrospective, requiring the recall of previous mental events from sleep on awakening. Thus, it is possible that dreaming occurs throughout sleep and differences in subsequent dream reports are owing to systematic differences in our ability to recall mentation on awakening. For this reason, it cannot be concluded with certainty that sleep (...) cognition is more predominant or in any way different during REM compared to NREM sleep. It is our contention that REM sleep and ponto-geniculo-occipital (PGO) waves do not necessarily represent stimulation of the cortex in the generation of dreams, but might rather represent enhanced arousal of attention mechanisms during sleep, which results in the subsequent recall of attended mentation on awakening. (shrink)

This volume presents cutting-edge theory and research on emotions as constructed events rather than fixed, essential entities. It provides a thorough introduction to the assumptions, hypotheses, and scientific methods that embody psychological constructionist approaches. Leading scholars examine the neurobiological, cognitive/perceptual, and social processes that give rise to the experiences Western cultures call sadness, anger, fear, and so on. The book explores such compelling questions as how the brain creates emotional experiences, whether the "ingredients" of emotions also give rise to (...) other mental states, and how to define what is or is not an emotion. Introductory and concluding chapters by the editors identify key themes and controversies and compare psychological construction to other theories of emotion. (shrink)

Neuroscientists now approach some of the deepest problems of the human condition - from illnesses and disorders such as Alzheimer's disease and schizophrenia, to the search for the nature of consciousness itself - in the belief that their science can say something useful about these processes and how to intervene in them. At the same time, by addressing the biological mechanisms involved in phenomena as varied as street violence, drug addiction and sexual orientation, the new science raises profound ethical, legal, (...) social and medical questions. Over many of these issues there is no clear consensus but rather, intense debate. Is memory a molecular process? Is schizophrenia a genetic disorder? What does the future hold for psychopharmacology? Can consciousness be computed and is artificial intelligence a real prospect? From Brains to Consciousness? brings together fourteen of the world's leading neuroscientists, psychologists, computer modellers and philosophers, in a series of chapters that offer fascinating and up-to-the-minute insight into the debates that are taking place in this exciting area of research. (shrink)

We propose that Mealey's model is limited in its description of sociopathy because it does not provide an adequate role for the main organ mediating genes and behavior, namely, the brain. Further, on the basis of our research, we question the view of sociopaths as a homogeneous group.

This special issue of JET deals with questions relating to our radically enhanced future selves or our possible “mind children” – conscious beings that we might bring about through the development of advanced computers and robots. Our mind children might exceed human levels of cognition, and avoid many human limitations and vulnerabilities. In a call for papers earlier this year, the editors asked how far we ought to go with processes that might ultimately convert humans to some sort of post-biological (...) form or replace us with post-biological beings. Are these coherent ideas at all? If so, is it likely, or plausible, that we’ll one day be able to do such things? Even if we can, is that desirable? More generally, how far can all these processes go, and how far should we pursue them? To offer a more personal and pointed question, would you “upload” your personality into some kind of advanced computer or robot if the technology became available? Would you do so even if the process required the destruction of your original organic brain? We are not the first to ask such questions. A large body of relevant literature has built up in recent decades, some of it discussing these and similar questions purely as philosophical thought experiments , but some of it at the level of practical recommendations for a posthuman future. Despite the intensity and quality of the ongoing debate and the eminence of many of the contributors, much work remains to be done to sort it all out and advance the discussion. We have gathered a range of viewpoints, and I predict that some of these pieces will soon be regarded as classics. They may not be the last word – how could they be when they do not all agree with each other? – but they advance our understanding of what is at stake. (shrink)

"Well-publicized research in psychology tells us that over half of our attempts to change habitual behavior fail within one year. Even without reading the research, most of us will intuitively sense the truth in this, as we have all tried and failed to rid ourselves of one bad habit or another. The human story of habits and the difficulty of change has been told in many books - most of which will make only a quick reference to dopamine or the (...) "lizard brain" before moving on to practical tips and tricks for behavior change. In contrast, Stuck: The Neuroscience of Why Changing Our Behavior is So Hard will tell the brain's story about why behavior is so hard to change. Russell Poldrack offers an in-depth, yet entirely accessible, guide to the neuroscientific research on habits and habit change. Part I introduces the "anatomy of a habit," starting with the argument that the resilience of our habits stems largely from a mismatch between the environment in which our brains evolved and the one in which we now live, and continuing on to introduce current work on fear and anxiety, motivation, and cognitive control that bears on habit formation. Part II focuses on what neuroscience can tell us about breaking habits, introducing evidence-based strategies that give us the best possible chance to break cycles of bad behavior. Throughout the book, Poldrack offers a clear-eyed view of what neuroscience can tell us about habit change, and what it cannot - and importantly, how we know what we know"--. (shrink)

Carruthers views unsymbolized thinking as and, therefore, as a potential threat to his mindreading-is-prior position. I argue that unsymbolized thinking may involve (non-symbolic) sensory aspects; it is therefore not purely propositional, and therefore poses no threat to mindreading-is-prior. Furthermore, Descriptive Experience Sampling lends empirical support to the view that access to our own propositional attitudes is interpretative, not introspective.

What degrees of belief does Sleeping Beauty's evidence support? That depends.

Galatea, or the Future of Darwinism W Russell Brain Originally published in 1927 "A brilliant exposition…of the evolutionary hypothesis." The Guardian "Should prove invaluable…" Literary Guide This non-technical but closely-reasoned book is a challenge to the orthodox teaching on evolution known as Neo-Darwinism. The author claims that although Neo-Darwinian theories can possibly account for the evolution of forms, they are quite inadequate to explain the evolution of functions. 88pp ************** Daedalus or Science and the Future J B S (...) Haldane Originally published in 1924. "The essay is brilliant. Sparkling with wit and bristling with challenges." British Medical Journal "Predicts the most startling changes." Morning Post This volume examines the future of scientific research from religious, philosophical social and economic standpoints. 94pp Automaton, or the Future of Mechanical Man H Stafford Hatfield Originally published in 1928 "It is impossible to do justice to his volume in a brief review…"Daily Herald At the time of original publication mankind’s chief inventions had been extensions of his senses or limbs. This work prophesies the dawn of an era in which substitutes will gradually be found even for the human brain. 96pp Gallio or the Tyranny of Science J W N Sullivan Originally published in 1927 "So packed with ideas it is not possible to give any adequate résumé of its contents." Times Literary Supplement "Remarkable monograph…devastating summary of materialism…" Spectator An attack on the values which science is so successfully imposing upon civilization. 90pp. (shrink)

This introductory chapter provides an overview of the content discussed in the subsequent chapters of the book. Machine or artificial intelligence (AI), might well have the ability to understand, modify, and improve its own source code, carrying it by great leaps into domains of ability that unaided flesh can never hope to reach. AI uses engineered electronic or photonic neural nets operating a million times faster. Uploading need not imply a world of bloated grubs lying in the dark with their (...) brains wired to spreadsheets and simulated worlds. The initial goal of uploaders would be to emulate and enhance the brain, and that requires rich connections to external reality. The artificial system is not merely simulating but actually emulating or replicating the relevant functioning of a human brain. The book shows enthusiasm about the prospects of machine intelligence and mind uploading, and expresses skepticism or concern. (shrink)

The medical specialty of psychiatry should possess a basic science in which pathologies are considered deviations from normal brain physiology. Historically, psychoanalytic pathogenesis was considered separately from brain physiology. It was not scientific because observations could not be refuted. Countering this, Eli Robins's legacy stemmed partly from his having been damaged by a psychoanalyst. It eschewed pathogenesis. Attempting to integrate psychiatry with medicine more generally, Robins and colleagues refocused on empiricism, although they acknowledged the brain's centrality. Here (...) I hold that the term biology used in the context of psychiatry should broadly encompass social facets of organismal function. The term sociophysiology may best describe the central basic science of psychiatry because it alludes to brain functions used for the person's social realm. Disruptions of such functions result in deviant behaviors and unpleasant feelings which psychiatrists diagnose and treat. Future study encompassing top-down and bottom-up research should include genome-neural-behavioral analyses. (shrink)

The medical specialty of psychiatry should possess a basic science in which pathologies are considered deviations from normal brain physiology. Historically, psychoanalytic pathogenesis was considered separately from brain physiology. It was not scientific because observations could not be refuted. Countering this, Eli Robins's legacy stemmed partly from his having been damaged by a psychoanalyst. It eschewed pathogenesis. Attempting to integrate psychiatry with medicine more generally, Robins and colleagues refocused on empiricism, although they acknowledged the brain's centrality. Here (...) I hold that the term biology used in the context of psychiatry should broadly encompass social facets of organismal function. The term “sociophysiology” may best describe the central basic science of psychiatry because it alludes to brain functions used for the person's social realm. Disruptions of such functions result in deviant behaviors and unpleasant feelings which psychiatrists diagnose and treat. Future study encompassing top-down and bottom-up research should include genome-neural-behavioral analyses. (shrink)

I selectively and critically review the state of knowledge about human evolution and the place of humans vis-à-vis living apes, with emphasis on bipedal posture and locomotion, expansion of the brain and associated cognitive capacities, speech, tool behavior, culture, and society. I end with a personal perspective on God and Heaven.